Effect of cyclodextrin complexation on phenylpropanoids’ solubility and antioxidant activity
نویسندگان
چکیده
منابع مشابه
Effect of cyclodextrin complexation on phenylpropanoids’ solubility and antioxidant activity
The complexation abilities of five cyclodextrins (CDs) with seven phenylpropanoids (PPs) were evaluated by UV-visible spectroscopy, phase solubility studies and molecular modeling. Formation constants (K f), complexation efficiency (CE), PP:CD molar ratio, increase in formulation bulk and complexation energy were assessed. All complexes exhibited a 1:1 stoichiometry but their stability was infl...
متن کاملantioxidant and antimicrobial activity of allium jesdianum extract
چکیده بررسی فعالیت ضد اکسیدانی و ضدمیکروبی عصاره گیاه بن سرخ (allium jesdianum) به کوشش: زهرا مقیمی هدف از این تحقیق بررسی میزان ترکیبات فنولی کل، ترکیبات فلاوونوئیدی کل، فعالیت ضداکسیدانی و ضدمیکروبی عصاره ی گیاه تازه و خشک بن سرخ بود. استخراج عصاره به روش های غوطه وری، استفاده از همزن مغناطیسی، دستگاه مایکروویو، امواج فراصوت و گرمادهی مقاومتی و با استفاده از متانول، اتانول و آب به عنوا...
Effect of β-Cyclodextrin Complexation on Solubility and Enzymatic Conversion of Naringin
In the present paper, the effect of beta-cyclodextrin (beta-CD) inclusion complexation on the solubility and enzymatic hydrolysis of naringin was investigated. The inclusion complex of naringin/beta-CD at the molar ratio of 1:1 was obtained by the dropping method and was characterized by differential scanning calorimetry. The solubility of naringin complexes in water at 37 ± 0.1 °C was 15 times...
متن کاملEffect of β Cyclodextrin Complexation on the Solubility and Dissolution Rate of Carbamazepine from Tablets
Carbamazepine was complexed with β-cyclodextrin in an attempt to enhance the solubility features of the drug. Phase solubility studies revealed a linear relationship between carbamazepine solubility and β-cyclodextrin concentration. The 3value of the stability constant (405.42 M) calculated from the phase solubility diagram indicated that the complexes were adequately stable. Carbamazepine-β-cy...
متن کاملEffect of Pvp on Cyclodextrin Complexation of Efavirenz for Enhancing Its Solubility and Dissolution Rate
Efavirenz belongs to Class II under BCS and exhibit low and variable bioavailability due to its poor aqueous solubility. As such it needs enhancement in the dissolution rate and bioavailability to derive its maximum therapeutic efficacy. The objective of the present investigation is to study the complexation of efavirenz with two cyclodextrins, βcyclodextrin (βCD) and hydroxypropyl β-cyclodextr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Beilstein Journal of Organic Chemistry
سال: 2014
ISSN: 1860-5397
DOI: 10.3762/bjoc.10.241